Liver involvement in endocrine diseases.
10.3760/cma.j.cn501113-20220318-00123
- VernacularTitle:内分泌系统疾病的肝脏表现
- Author:
Qian Yi WANG
1
,
2
;
Xiao Juan OU
1
,
2
;
Ji Dong JIA
1
,
2
Author Information
1. Liver Research Center, Beijing Friendship Hospital, Capital Medical University
2. Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis & National Clinical Research Center for Digestive Diseases, Beijing 100050, China.
- Publication Type:Journal Article
- MeSH:
Cholestasis/pathology*;
Endocrine System Diseases/pathology*;
Hepatitis, Autoimmune/pathology*;
Humans;
Liver/pathology*;
Liver Diseases/pathology*
- From:
Chinese Journal of Hepatology
2022;30(4):352-356
- CountryChina
- Language:Chinese
-
Abstract:
As a secondary endocrine organ, the liver is closely related to the endocrine system. Liver involvement is not uncommon in endocrine diseases, such as hyper/hypothyroidism, diabetes, dysfunction of adrenal and gonadal. It can be manifested in a variety of forms, including hepatocyte injury (elevated transaminase), bile duct injury (cholestasis), hepatocyte steatosis, vascular injury and liver tumor. Direct and indirect liver injury caused by abnormal hormone levels and side effects of drugs for the treatment of endocrine diseases are common pathogenesis. In addition, endocrine diseases can be concomitant with liver diseases, such as autoimmune thyroiditis and autoimmune hepatitis. Systemic diseases can also involve the endocrine system and liver at the same time, such as systemic lupus erythematosus and IgG4 related diseases. For patients with unexplained liver injury, endocrine system diseases should be considered as the differential diagnosis.
