Current status, challenges and reflections on stem cell therapy for liver diseases.
10.3760/cma.j.cn501113-20220221-00079
- Author:
Chang Cun GUO
1
;
Ying HAN
1
Author Information
1. Department of Gastroenterology, the First Affiliated Hospital, Air Force Medical University, Xi'an 710032, China.
- Publication Type:Review
- MeSH:
Cell- and Tissue-Based Therapy;
Humans;
Liver Cirrhosis/therapy*;
Liver Diseases/therapy*
- From:
Chinese Journal of Hepatology
2022;30(3):233-236
- CountryChina
- Language:Chinese
-
Abstract:
There are increasing number of clinical studies on the use of stem cells in the treatment of liver diseases. Most studies have shown that stem cells can significantly improve liver function and prolong survival in patients with decompensated cirrhosis and liver failure. However, the current study has high heterogeneity and few mechanistic research data, which cannot answer many key questions about stem cell therapy for liver diseases. This paper reviews the research status of stem cells, in order to clarify the existing problems and challenges, and puts forward some reflections and countermeasures, with hope to promote the clinical application of stem cells in the treatment of liver diseases.
