Clinicopathological characteristics and differential diagnosis of 6 cases of congenital granular cell tumor.
10.3760/cma.j.cn112144-20210811-00361
- Author:
Long CHENG
1
;
Kun FU
1
;
Ning GAO
1
;
Jing Hua CAI
1
;
Wei Jing XU
1
;
Kang Yan LIU
1
;
Han LU
1
;
Xin Quan LYU
2
;
Li WANG
2
;
Wei HE
1
Author Information
1. Department of Oral and Maxillofacial Surgery, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
2. Department of Pathology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, China.
- Publication Type:Journal Article
- MeSH:
Child;
Diagnosis, Differential;
Female;
Gingival Neoplasms/surgery*;
Granular Cell Tumor/surgery*;
Humans;
Male;
Pregnancy
- From:
Chinese Journal of Stomatology
2022;57(4):410-414
- CountryChina
- Language:Chinese
-
Abstract:
To provide references for the diagnosis and treatment of congenital granular cell tumor (CGCT), by comprehensive analysis of the clinical data, histopathological and immunohistochemical results. Patients with CGCT were involede, from March 2015 to November 2020, at the Department of Oral and Maxillofacial Surgery of the First Affiliated Hospital of Zhengzhou University. A total of 6 children, aged 3-16 days, 1 male and 5 female, 5 maxillary and 1 mandibular, with maximum tumor diameter of 6-70 mm, were included. The lesions of CGCT were single and connected to the alveolar ridge by a pedicle. The surface of the tumor was covered with a vascular network, and two cases had ulcers on the surface of the tumor. All 6 cases had the tumor removed surgically and there was no recurrence or metastasis in the follow-up visit. Although CGCT is rare, it is a benign tumor and generally does not recur or metastasize after surgery, and has a good prognosis. The prenatal imaging, clinical manifestations after delivery, pathological characteristics and immunohistochemical analyses may provide reference for early diagnosis and treatment of CGCT.
