Meta-analysis on the contents of trace elements in workers with occupational exposure to lead.
10.3760/cma.j.cn121094-20210207-00085
- Author:
Ling ZHANG
1
;
Si Wei TAN
1
;
Ji SHAO
1
;
Yan Peng SHI
1
;
Ke Wen SU
1
;
Xiao Yue SHAN
1
;
Hai Peng YE
1
Author Information
1. Hangzhou Hospital for Prevention and Treatment of Occupational Disease, Department of Sanitation Test, Hangzhou 310014, China.
- Publication Type:Meta-Analysis
- Keywords:
Lead;
Meta analysis;
Occupational exposure;
Trace elements
- MeSH:
Copper;
Humans;
Iron;
Lead;
Manganese;
Occupational Exposure;
Trace Elements;
Zinc
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(5):347-353
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To quantitatively evaluate the content differences of trace elements in workers with occupational exposure to lead. Methods: In January 2021, relevant literatures on the contents of trace elements in workers with occupational exposure to lead published from 1990 to 2020 were searched through CNKI, Wanfang, VIP, PubMed, web of science and Embase. Screened and extracted the literatures, and evaluated the quality of the included literatures with Newcastle Ottawa Scale. Meta analysis was performed with Review Manager 5.3 software, and standardized mean difference (SMD) and its 95% confidence interval were used as effect indicators. Results: A total of 20 literatures were included, and the quality scores were 5-7. The results of Meta-analysis showed that compared with the control group, the contents of blood zinc (SMD=-1.01, 95%CI: -1.53, -0.49) , hair zinc (SMD=-0.17, 95%CI: -0.33, -0.01) , hair copper (SMD=-0.50, 95%CI: -1.01, 0) , hair iron (SMD=-3.91, 95%CI: -5.80, -2.03) and hair manganese (SMD=-1.09, 95%CI: -2.02, -0.15) in occupational lead exposure group were significantly lower (P<0.05) . Compared with the control group, the content of cobalt in hair of occupational lead exposure group (SMD=1.41, 95%CI: 0.72, 2.10) was higher, and the difference was statistically significant (P<0.05) . There was no significant difference in the contents of blood chromium, blood copper, blood iron, blood manganese, blood selenium and hair nickel between the two groups (P>0.05) . Conclusion: Workers with occupational exposure to lead have abnormal trace elements.
