The method of determination for butyronitrile and isobutyronitrile in the air of workplace by dissolved desorption-gas chromatography.
10.3760/cma.j.cn121094-20210119-00034
- Author:
Guan Lin CHEN
1
;
Song Gen CHEN
1
;
Wei Feng RONG
2
;
Jia Heng HE
2
;
Jian Yi LIANG
1
;
Xue Qiong ZHOU
3
Author Information
1. Laboratory Department, Foshan Institute of Occupational Disease Prevention and Control, Foshan 528000, China.
2. Institute of Toxic Chemical Surveillance, Guangdong Province Hospital for Occupational Disease Prevention and Treatment, Guangzhou 510300, China.
3. School of Public Health, Southern Medical University, Guangzhou 510515, China.
- Publication Type:Journal Article
- Keywords:
Air;
Butyronitrile;
Chromatography, gas;
Isobutyronitrile;
Solvent desorption;
Workplace
- MeSH:
Air Pollutants, Occupational/analysis*;
Chromatography, Gas/methods*;
Nitriles;
Workplace
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(4):296-299
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To establish a method for the determination of butyronitrile and isobutyronitrile in the air of workplace by gas chromatography. Methods: In March 2020, butyronitrile and isobutyronitrile in the air of workplace was collected by silica gel, eluted with methanol, separated and determined by gas chromatogram with flame ionization detector, the characteristics of determination of nitrile and isobutyronitrile by gas chromatography were analyzed. Results: The limit of detection for butyronitrile and isobutyronitrile was 0.33 μg/ml. The linear range of butyronitrile determined by this method was 1.60-1600.00 μg/ml, y=2.295x-3.480, and the coefficient correlation was 0.99998, and the minimum detection concentration was 0.22 mg/m(3) (collected sample volume was 1.50 L) . The within-run precisions were 2.43%-4.12%, the between-run precisions were 1.72%-3.70%, and the desorption rates were 93.26%-98.41%. The linear range of isobutyronitrile determined by this method was 1.52-1520.00 μg/ml, y=2.208x-0.102, and the coefficient correlation was 0.99998, and the minimum detection concentration was 0.22 mg/m(3) (collected sample volume was 1.50 L) . The within-run precisions were 2.52%-3.22%, the between-run precisions were 1.20%-3.82%, and the desorption rates were 96.85%-102.50%. The sealed samples could be stored at least 10 days at room temperature without significant loss. Conclusion: The method has the advantages of good precision, high sensitivity and simple operation. It is suitable for the simultaneous determination of butyronitrile and isobutyronitrile in the air of workplace.
