Research progress on the role of lncRNA in the occurrence and development of malignant mesothelioma.
10.3760/cma.j.cn121094-20210413-00205
- Author:
Ming Ying JIN
1
;
Zhao Qiang JIANG
1
Author Information
1. Hangzhou Medical College (Zhejiang Academy of Medical Sciences), School of Public Health (Institute of Hygiene, Institute of Occupational Disease Control), Hangzhou 310013, China.
- Publication Type:Review
- Keywords:
Diagnosis;
LncRNA;
Mesothelioma;
Prognosis
- MeSH:
Asbestos;
Epigenesis, Genetic;
Humans;
Mesothelioma/genetics*;
Mesothelioma, Malignant;
Prognosis;
RNA, Long Noncoding/genetics*
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(3):231-235
- CountryChina
- Language:Chinese
-
Abstract:
Malignant mesothelioma (MM) is a long latency, poor prognosis and asbestos exposure related malignant disease. Long non-coding RNA (lncRNA) is a kind of RNA with a length of more than 200 nucleotides that does not encode protein. It plays an important role in epigenetic regulation, cell cycle regulation and cell differentiation regulation. Recent studies have shown that the abnormal expression or function of lncRNA is closely related to the diagnosis and prognosis of MM. In this paper, the lncRNA research on MM is reviewed to better understand the role of lncRNA in MM.
