Relationship between pesticide exposure and lipid metabolism in population.
10.3760/cma.j.cn121094-20210126-00053
- Author:
Teng Long YAN
1
;
Xiao Jun ZHU
2
;
Hui Hua DU
1
;
Xiao Wen DING
1
;
Dong Sheng NIU
1
;
Jue LI
1
Author Information
1. Beijing Institute of Occupational Disease Prevention and Treatment, Beijing 100093, China.
2. National Center for Occupational Safety and Health, National Health Commission of the People's Republic of China, Beijing 102308, China.
- Publication Type:Journal Article
- Keywords:
Herbicide;
Insecticide;
Lipid metabolism;
Pesticide
- MeSH:
Adult;
Cholesterol, HDL;
Cholesterol, LDL;
Female;
Humans;
Lipid Metabolism;
Male;
Middle Aged;
Nutrition Surveys;
Pesticides;
Young Adult
- From:
Chinese Journal of Industrial Hygiene and Occupational Diseases
2022;40(1):24-27
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the effect of pesticides and herbicides on lipid metabolism. Methods: In November 2020, Based on the data of the national health and Nutrition Survey (NHANES) (2011-2014) , select the population aged 20~65 who have demographic information, pesticide use and data of four lipid metabolism indicators [total cholesterol (TC) , triglyceride (TG) , high density lipoprotein cholesterol (HDLC) and low density lipoprotein cholesterol (LDLC) ] (n=3039) . The subjects were divided into insecticide group (320 people) and non insecticide group (2719) according to the use of insecticides, and herbicide group (156 people) and non herbicide group according to the use of herbicides. Results: Among the 3039 subjects, the males and female were 1509 (49.7%) and 1530 (50.3%) respectively. The males age was (39.7±12.0) years and the females age was (40.2±12.0) years The concentration of HDLC in the NHANES (55.4±15.0) mg/dl was lower than that of (58.2±14.2) mg/dL in the non herbicide group (P<0.05) (b=-0.044, P<0.05) . The results showed that the use of herbicides was related to the decrease of HDLC and the increase of LDLC and LDLC/HDLC in female population (b=-0.050, 0.062, 0.067, all P<0.05) . Conclusion: Herbicide exposure can cause the change of lipid metabolism, and the effect on female population is more obvious.
