A Case of Acute Disseminated Encephalomyelitis Associated with Hepatitis C Virus Infection.
10.3349/ymj.2012.53.4.856
- Author:
Jae Eun SIM
1
;
Jun Bum LEE
;
Yu Na CHO
;
Sang Hyun SUH
;
Ja Kyung KIM
;
Kyung Yul LEE
Author Information
1. Department of Neurology, Severance Institute for Vascular and Metabolic Research, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. kylee@yuhs.ac
- Publication Type:Case Reports
- Keywords:
Acute disseminated encephalomyelitis;
hepatitis C virus;
autoimmunity;
direct viral invasion;
anti-HCV antibody
- MeSH:
Encephalomyelitis, Acute Disseminated/*diagnosis/drug therapy/etiology/virology;
Female;
Hepacivirus/pathogenicity;
Hepatitis C/*complications;
Humans;
Methylprednisolone/therapeutic use;
Middle Aged
- From:Yonsei Medical Journal
2012;53(4):856-858
- CountryRepublic of Korea
- Language:English
-
Abstract:
Acute disseminated encephalomyelitis (ADEM) is a monophasic autoimmune demyelinating disease of the central nervous system, which typically follows acute viral or bacterial infection or vaccination. We report a case of ADEM associated with hepatitis C virus (HCV) infection with positive serum and cerebrospinal fluid (CSF) anti-HCV antibody. After steroid treatment, neurologic symptoms were improved. Virus triggers autoimmunity or direct viral invasion plays a part in the genesis of ADEM. This is the first reported case of ADEM with anti-HCV antibody in the CSF.
