Progress in research of 2019-nCoV Omicron variant.
10.3760/cma.j.cn112338-20220121-00061
- Author:
Yun HUANG
1
;
Yi Hong LI
1
;
Shi La XIE
2
;
Zu Hua RONG
3
;
Bo Sheng LI
4
;
Min KANG
1
;
Ai Ping DENG
1
;
Yan LI
5
Author Information
1. Institute for Communicable Disease Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
2. Institute for AIDS Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
3. Guangdong Provincial Institute of Public Health, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
4. Institute of Pathogenic Microbiology, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
5. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
- Publication Type:Journal Article
- MeSH:
COVID-19;
Humans;
Mutation;
Pandemics;
SARS-CoV-2
- From:
Chinese Journal of Epidemiology
2022;43(5):655-662
- CountryChina
- Language:Chinese
-
Abstract:
2019-nCoV Omicron (B.1.1.529) variant, which has brought new challenges to the prevention and control of COVID-19 pandemic, has the characteristics of stronger transmissibility and more rapid transmission and more significant immune evasion. It took only two months to become a predominant strain worldwide after its identification in South Africa in November 2021. Local epidemics caused by Omicron variant have been reported in several provinces in China. However, the epidemiological characteristics of highly mutated Omicron variant remain unclear. This article summarizes the progress in the research of functional mutations, transmissibility, virulence, immune evasion and cross-reactive immune responses of Omicron variant, to provide references for the effective prevention and control of COVID-19 pandemic caused by Omicron variant.