Progress in prevention and control of Nipah virus disease.
10.3760/cma.j.cn112338-20210706-00529
- Author:
Huang Fang SHU
1
;
Ke Yi WANG
1
;
She Lan LIU
2
;
Meng ZHANG
3
;
Tie SONG
4
Author Information
1. School of Public Health, Guangdong Pharmaceutical University, Guangzhou 510315, China.
2. Department of Communicable Disease Control and Prevention, Zhejiang Provincial Center for Disease Control and Prevention, Hangzhou 310051, China.
3. Institute for Communicable Disease Control and Prevention, Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
4. Guangdong Provincial Center for Disease Control and Prevention, Guangzhou 511430, China.
- Publication Type:Systematic Review
- MeSH:
Animals;
Chiroptera;
Communicable Diseases, Emerging/prevention & control*;
Disease Outbreaks;
Henipavirus Infections/prevention & control*;
Nipah Virus;
Swine;
Zoonoses/prevention & control*
- From:
Chinese Journal of Epidemiology
2022;43(2):286-291
- CountryChina
- Language:Chinese
-
Abstract:
Nipah virus disease (NVD) is a newly emerged zoonosis with a case fatality rate of 40%-75%. NVD is a severe threat to human health and the development of livestock farming. NVD has become one of the emerging infectious diseases with great concern globally during more than 20 years. Nipah virus (NiV) is a pathogen for NVD, the natural host of which is Fruit bats of the Pteropodidae family. The clinical spectrum of NiV infection is broad, including asymptomatic infection, acute respiratory infection, fatal encephalitis, and even death. Since NiV was first identified in Malaysia in 1999, it has been prevalent mainly in Southeast Asia and South Asia. NiV is primarily transmitted to humans through bat-pig-human, contaminated food. Currently, there are no specific therapeutic drugs and vaccines for NVD. Although there are no cases of NVD reported in China, which has close personnel and trade exchanges with major NVD-endemic countries, and NiV antibody has also been detected in relevant bats. There is a potential risk of importing NVD and domestic outbreaks in the future in this country. This paper provides a systematic review of the research progress in the prevention and control of NVD etiology, epidemiology, clinical manifestations and laboratory diagnosis to help relevant staff to understand NVD more comprehensively and systematically.