Review on diagnosis and molecular characterization of Toxoplasma gondii in humans and animals
https://doi.org/10.47665/tb.38.4.091
- Author:
Uddin, A.H.M.M.
1
;
Hossain, D.
2
;
Ahsan, M.I.
3
;
Atikuzzaman, M.
1
;
Karim, M.R.
4
Author Information
1. Department of Surgery and Theriogenology, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh
2. Department of Medicine and Public Health, Faculty of Animal Science and Veterinary Medicine, Sher-e-Bangla Agricultural University, Dhaka 1207, Bangladesh
3. Department of Epidemiology and Public Health, Faculty of Veterinary, Animal and Biomedical Sciences, Sylhet Agricultural University, Sylhet 3100, Bangladesh
4. Department of Medicine, Faculty of Veterinary Medicine and Animal Science, Bangabandhu Sheikh Mujibur Rahman Agricultural University, Gazipur 1706, Bangladesh
- Publication Type:Journal Article
- Keywords:
Toxoplasma gondii;
diagnosis;
genetic characterization;
humans;
animals
- From:Tropical Biomedicine
2021;38(No.4):511-539
- CountryMalaysia
- Language:English
-
Abstract:
Toxoplasma gondii is an obligate intracellular protozoon which causes toxoplasmosis, an
important zoonotic disease that is endemic worldwide. Common sources of T. gondii infection
in humans are food or water contaminated with oocysts and raw or undercooked meat with
cysts. In animals, common sources of infection include feed, water, or litter contaminated
with oocysts. The diagnosis and molecular characterization of T. gondii infection in humans
and animals is crucial due to public and veterinary health importance. Various traditional
and serological methods have been used in clinical practice for toxoplasmosis diagnosis,
but interpreting the results remains a challenge. Several molecular techniques have also
been used for the detection and genetic characterization of T. gondii, but primarily in research
settings. In this paper, we review the techniques that are currently used for the diagnosis
and genetic characterization of T. gondii in humans and animals, along with their advantages
and disadvantages. The techniques reviewed have laid the groundwork for the future
development of more effective and precise detection and characterization of T. gondii. These
advances will contribute to a better understanding of epidemiology, prevention and control
of toxoplasmosis. Thus, this review would be of particular interest to clinical physicians,
veterinarians and researchers.
- Full text:8.2021my1296.pdf
