Research progress on basic fibroblast growth factor in promoting periodontal tissue regeneration
- Author:
ZHANG Peipei
1
;
LI Hongyan
1
;
TIAN Yue
1
;
CHEN Huishan
1
;
LIN Hongbing
1
;
SHEN Yuqin
1
Author Information
- Publication Type:Review
- Keywords: basic fibroblast growth factor; inflammation control; migration; proliferation; angiogenesis; periodontal ligament-like tissue; osteogenesis/cementum; periodontal tissue regeneration; periodontal disease
- From: Journal of Prevention and Treatment for Stomatological Diseases 2022;30(10):757-760
- CountryChina
- Language:Chinese
- Abstract: Basic fibroblast growth factor (bFGF) exhibits superior biological functions by improving periodontal inflammation, promoting the migration and proliferation of periodontal-related stem cells, promoting the formation of blood vessels and periodontal ligament-like tissue, and regulating the formation of bone/cementum. It plays an important role in tooth development, repair and regeneration. bFGF can be combined with seed cells and scaffold materials for periodontal tissue regeneration, which has been verified in a number of experimental studies. However, the application of bFGF alone as a drug in clinical treatment requires further research.
- Full text:碱性成纤维细胞生长因子与牙周组织再生的研究进展.pdf
