Mechanisms and therapeutic drugs of high-altitude lung diseases
10.12206/j.issn.1006-0111.202111025
- VernacularTitle:高原肺部疾病的发病机制及治疗药物
- Author:
Yueqi HUANG
1
;
Jinglu HU
2
,
3
;
Qi LI
2
,
4
;
Miao LI
1
;
Fei XIE
5
;
Lina DU
2
,
4
,
6
;
Yiguang JIN
2
,
3
Author Information
1. Beijing Institute of Radiation Medicine, Beijing 100850, China.
2. Beijing Institute of Radiation Medicine, Beijing 100850, China
3. Pharmaceutical College, Henan University, Kaifeng 475004, China.
4. Department of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan 250355, China.
5. Department of Respiratory and Critical Care Medicine, the Eighth Medical Center, General Hospital of the PLA, Beijing 100193, China.
6. Pharmaceutical College, Henan University, Kaifeng 475004, China
- Keywords:
high-altitude pulmonary edema;
high-altitude pulmonary artery hypertension;
high-altitude de-adapted reaction
- From:
Journal of Pharmaceutical Practice
2022;40(4):289-295
- CountryChina
- Language:Chinese
-
Abstract:
The heavily harsh plateau environment including low pressure, hypoxia, cold, dryness and strong ultraviolet radiation, seriously threatens the physical and mental health of those who quickly enter the plateau area. Lungs are the sensitive organs for high altitude injury. High-altitude lung diseases include the acute high-altitude lung disease (i.e., high-altitude pulmonary edema), the chronic high-altitude lung disease (i.e., high-altitude pulmonary artery hypertension) and the high-altitude de-adapted reaction. This review summarizes the pathogenic mechanisms and the main therapeutic drugs of high-altitude lung diseases based on the recent research. Moreover, the related formulations and administration routes are also reviewed here. It will provide support and counsel for the diagnosis and treatment of high-altitude lung diseases.
