Clinicopathological and magnetic resonance imaging characteristics analysis of cardiac tumors in children
10.3760/cma.j.cn115355-20210626-00278
- VernacularTitle:儿童心脏肿瘤临床病理学及磁共振成像影像学特征分析
- Author:
Biao WANG
1
;
Jinhua CAI
;
Juan BAI
;
Lijuan WEI
;
Siqi ZHANG
;
Shuming XU
Author Information
1. 山西医科大学研究生院，太原 030001
- Keywords:
Heart neoplasms;
Child;
Pathological conditions, signs and symptoms;
Magnetic resonance imaging
- From:
Cancer Research and Clinic
2022;34(1):56-60
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate clinicopathological and magnetic resonance imaging (MRI) characteristics of pediatric cardiac tumors.Methods:The clinical, pathological and MRI data of 7 patients with pediatric cardiac tumors confirmed by pathological examination in Children's Hospital of Chongqing Medical University from February 2012 to December 2016 were retrospectively analyzed.Results:There were 3 males and 4 females with first diagnosis age ranging from 1 month to 3 years. As for clinical presentation, most cases were featured with cardiac murmur and enlarged cardiac boundary; only 1 case had acute cerebral infarction, and 1 case did not show any abnormal performance. Pathological findings showed that 6 cases of benign tumors (including 2 cases of fibroma, 1 case of rhabdomyoma, 1 case of myxoma, 1 case of lipoma and 1 case of hemangioma), 1 case of malignant tumor (primitive neuroectodermal tumor of pericardium). MRI results showed that the signal intensity of malignant tumor was higher than that of normal myocardium in each sequence; significant differences were found in benign tumors; first-pass perfusion, cardiac cine image and late gadolinium enhancement were the most obvious.Conclusions:The clinical presentations of pediatric cardiac neoplasms are atypical. Each tumor type has pathognomonic pathological features. MRI has great advantages in the diagnosis and differential diagnosis of cardiac tumors especially for benign tumors.
