Clinical study of acupuncture plus Dang Gui Bu Xue Qu Feng Tang for benign essential blepharospasm
- VernacularTitle:针刺结合当归补血祛风汤治疗特发性眼睑痉挛的临床研究
- Author:
Yuelan ZOU
;
Xiehe KONG
;
Xiaocong GUO
;
Xuejun WANG
;
Xiaoying LI
;
Rong HAN
;
Xiaopeng ZHANG
;
Guang YANG
;
Yanting YANG
;
Xiaopeng MA
- Keywords:
Acupuncture Therapy;
Acupuncture Medication Combined;
Chinese Herbal Drugs;
Dang Gui Bu Xue Qu Feng Tang;
Blepharospasm;
Clinical Trial
- From:
Journal of Acupuncture and Tuina Science
2022;20(1):79-86
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To evaluate the therapeutic efficacy of acupuncture plus Dang Gui Bu Xue Qu Feng Tang for benign essential blepharospasm (BEB). Methods: A prospective randomized controlled trial was performed. A total of 105 participants were randomized 1:1:1 into an acupuncture group, a herbal medicine group and an acupuncture plus herbal medicine group. Participants in the acupuncture group received manual acupuncture treatment, twice a week. Participants in the herbal medicine group received Dang Gui Bu Xue Qu Feng Tang, oral administration, once a day. Participants in the acupuncture plus herbal medicine group received both treatments. The therapeutic effects of the three groups were evaluated after four weeks of treatment. The primary outcome was the Jankovic rating scale (JRS) score, and the secondary outcome was the blepharospasm disability index (BSDI) score. Results: After four weeks of treatment, the JRS total scores significantly decreased in all three groups versus baseline (P<0.05). A greater reduction in the JRS total score was reported in participants in the acupuncture plus herbal medicine group (P<0.05), but there was no significant difference between the acupuncture group and the herbal medicine group (P>0.05). The acupuncture plus herbal medicine group had a greater decrease in the JRS severity score than the herbal medicine group (P<0.05). The reduction in the JRS frequency score was not significantly different among the three groups (P>0.05). The BSDI scores significantly decreased in all three groups versus baseline (P<0.05), but the reduction in the BSDI score was insignificantly different among the three groups (P>0.05). Conclusion: It is effective in the treatment of BEB either to use acupuncture and Dang Gui Bu Xue Qu Feng Tang alone or in combination. The combination therapy shows a more significant effect than either of the treatment alone.
