Exacerbation of Lupus Nephritis in Pregnant Women with Remission of Lupus Nephritis.
10.4078/jrd.2013.20.5.314
- Author:
Ja Young JEON
1
;
Chang Hee SUH
;
Hyoun Ah KIM
;
Ju Yang JUNG
;
Jooho LEE
;
Eunjung KANG
;
Hyunee YIM
Author Information
1. Department of Rheumatology, Ajou Unversity School of Medicine, Suwon, Korea. chsuh@ajou.ac.kr
- Publication Type:Case Report
- Keywords:
Systemic lupus erythematosus;
Nephritis;
Pregnancy;
Flare;
Abortion
- MeSH:
Abortion, Induced;
Female;
Fertilization;
Humans;
Live Birth;
Lupus Erythematosus, Systemic;
Lupus Nephritis*;
Nephritis;
Pregnancy;
Pregnancy Outcome;
Pregnant Women*;
Proteinuria
- From:Journal of Rheumatic Diseases
2013;20(5):314-318
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder that predominantly affects women of reproductive age. Risk of SLE flare during pregnancy is dependent on disease activity of SLE and proteinuria at the time of conception, which affect pregnancy outcome. We report on three patients who developed renal flares during pregnancy after remission of lupus nephritis before pregnancy. Two patients were treated successfully, with pregnancy outcomes of live births however, another patient's pregnancy was terminated with induced abortion. For SLE patients, family planningis needed until disease activity of SLE has been stable for at least six months prior to the pregnancy. Nevertheless, flares of lupus could develop and influence maternal and fetal outcome. Therefore, renal flares during pregnancy should be recognized and treated immediately.
