Current status on the laboratory determination of advanced glycation end products
10.3760/cma.j.cn114452-20220112-00017
- VernacularTitle:晚期糖基化终末产物的研究现状
- Author:
Liqiao HAN
1
;
Jun YAN
;
Qiaoxuan ZHANG
;
Xianzhang HUANG
Author Information
1. 广东省中医院（广州中医药大学第二附属医院）检验医学部，广州 510120
- Keywords:
Clinical laboratory techniques;
Advanced glycation end products;
Glycometabolic disorders
- From:
Chinese Journal of Laboratory Medicine
2022;45(4):337-342
- CountryChina
- Language:Chinese
-
Abstract:
The concentration and accumulation rate of advanced glycation end products (AGEs) in the body are highly correlated with glycometabolic disorders. Therefore, the clinical detection of AGEs is of great value for the early diagnosis and prognostic evaluation of these diseases. However, due to the complexity of its structure, the diversity of glycosylation sites, and the limitations of existing detection methods, there is still a lack of widely available detection methods in clinical practice. Starting from the structure and classification of AGEs and the value of clinical testing, this article summarizes current status of various laboratory detection methods of AGEs, and the deficiencies and challenges of these testing methods, future directions are further prospected.
