Application progress of metabolomic analysis based on nuclear magnetic resonance spectroscopy in tumor diagnosis and treatment
10.3760/cma.j.cn114452-20210929-00609
- VernacularTitle:基于核磁共振波谱的代谢组学分析在肿瘤诊疗中的应用进展
- Author:
Zhuo LI
1
;
Na ZHANG
;
Pu XU
;
Xianfei ZENG
;
Xinyi HU
;
Xiaoke HAO
Author Information
1. 西安医学院第一附属医院检验科,西安 710077
- Keywords:
Nuclear magnetic resonance spectroscopy;
Tumor;
Metabolomics
- From:
Chinese Journal of Laboratory Medicine
2022;45(3):305-309
- CountryChina
- Language:Chinese
-
Abstract:
Nuclear magnetic resonance spectroscopy is one of the main analytical techniques for detecting metabolomics, which has the advantages of simple operation, rapid detection and non-invasive feature. By monitoring the changes of metabolites in the body, it is helpful to deeply understand the mechanism of disease and play a role in the diagnosis and treatment of diseases, but its clinical application has not yet been popularized. In recent years, the application of metabolomics in tumors has increasingly become a research hotspot. Therefore, in order to provide a reference for the research and clinical application of tumor metabolomics, the nuclear magnetic resonance spectroscopy and tumor metabolomics were introduced in this paper, and the application progress of metabolomics analysis based on this technique in early tumor screening, clinical diagnosis and prognosis evaluation were reviewed in this paper.