Therapeutic value of endoscopic submucosal dissection in the elderly with early colorectal cancer and precancerous lesion
10.3760/cma.j.cn321463-20210823-00385
- VernacularTitle:内镜黏膜下剥离术用于老年结直肠早期癌及癌前病变的治疗价值
- Author:
Zhenjun WEI
1
;
Shan TANG
;
Hui XIE
;
Yuli LIU
;
Fengyu WANG
;
Mingjie ZHANG
;
Xin WANG
;
Yuqi HE
Author Information
1. 解放军总医院第二医学中心保健七科，北京100700
- Keywords:
Colorectal neoplasms;
Aged;
Endoscopic submucosal dissection;
Early colorectal neoplasms;
Precancerous lesion
- From:
Chinese Journal of Digestive Endoscopy
2022;39(5):405-407
- CountryChina
- Language:Chinese
-
Abstract:
Clinical data of 210 patients with early colorectal cancer and precancerous lesion treated by endoscopic submucosal dissection (ESD) in the Digestive Endoscopy Center of the Seventh Medical Center of Chinese PLA General Hospital from January 2015 to March 2018 were collected and analyzed retrospectively. Patients were divided into two groups according to the age: the elderly group (≥65 years old, 100 cases) and the non-elderly group (<65 years old, 110 cases). The en bloc resection rate, complete resection rate,and curative resection rate of the elderly group were 92.0% (92/100), 91.0% (91/100) and 89.0% (89/100), respectively. The above indicators of the non-elderly group were 90.9% (100/110) ( P=0.972), 90.0% (99/110) ( P=0.991) and 88.2% (97/110) ( P=1.000), respectively. The incidence of intraoperative perforation in the elderly group was 4.0% (4/100) and in the non-elderly group was 6.4% (7/110) ( P=0.543). Delayed postoperative bleeding rate was 2.0% (2/100) in the elderly group, and 0 (0/110) in the non-elderly group ( P=0.226). ESD is effective and safe in treating early colorectal cancer and precancerous lesion in elderly patients.
