Efficacy of endoscopy for early nonampullary duodenal cancer
10.3760/cma.j.cn321463-20210712-00288
- VernacularTitle:内镜下治疗非壶腹部早期十二指肠癌的疗效分析
- Author:
Yongqiu WEI
1
;
Qiaozhi ZHOU
;
Peng LI
;
Ming JI
;
Yinglin NIU
;
Yongjun WANG
;
Shutian ZHANG
Author Information
1. 首都医科大学附属北京友谊医院消化内科 国家消化系统疾病临床医学研究中心 首都医科大学消化病学系 消化疾病癌前病变北京市重点实验室，北京 100050
- Keywords:
Duodenal neoplasms;
Endoscopic mucosal resection;
Endoscopic treatment;
Endoscopic submucosal dissection
- From:
Chinese Journal of Digestive Endoscopy
2022;39(5):394-398
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the clinical efficacy of endoscopic treatment for early nonampullary duodenal cancer.Methods:Data of patients with early nonampullary duodenal cancer, who underwent endoscopic treatment from January 2015 to January 2021 at Beijing Friendship Hospital were retrospectively analyzed. Baseline data, endoscopic treatment methods, wound closure, pathology, the occurrence and outcome of complications of patients were studied.Results:A total of 47 patients who successfully went through endoscopic treatment were enrolled. Seventeen cases received endoscopic mucosal resection (EMR), 5 cases received endoscopic submucosal dissection (ESD), and 7 cases received ESD+EMR (hybrid ESD). Six cases were converted to hybrid ESD due to difficulty in ESD. Four cases received full-thickness resection with over-the-scope clip system (OTSC), and 8 cases received endoscopic piecemeal mucosal resection (EPMR). Among the 47 cases of early cancer, the en bloc resection rate was 83.0% (39/47), and the complete resection rate was 85.1% (40/47). Four patients (8.5%) had perforation which occurred at the duodenal descending part during the perioperative period, among whom, 2 patients (4.3%) recovered after endoscopic treatment, 2 others (4.3%) recovered after surgical intervention. There were no complications such as postoperative bleeding or infection during the perioperative period.Conclusion:Endoscopic treatment for early nonampullary duodenal cancer is safe and effective. A specific treatment plan can be selected according to the location, size and specific conditions of the lesion. For the operation of the descending part, it is necessary to be more vigilant to against the occurrence of perforation complications.
