Enriched rehabilitation improves dual-task gait disorder after a transient ischemic attack
10.3760/cma.j.issn.0254-1424.2022.05.004
- VernacularTitle:丰富康复训练对短暂性脑缺血发作患者双重任务下步态障碍的影响
- Author:
Xin WANG
1
;
Yifeng QUAN
;
Xiaojia TANG
;
Hongyu ZHOU
;
Yicheng LYU
;
Nan SHI
;
Pin YAN
;
Junya WANG
Author Information
1. 扬州大学临床医学院康复医学科，扬州 225001
- Keywords:
Enriched rehabilitation training;
Ischemia;
Gait disorders;
Cognitive functioning
- From:
Chinese Journal of Physical Medicine and Rehabilitation
2022;44(5):402-406
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of enriched rehabilitation on dual-task gait disorder after a transient ischemic attack (TIA) and explore its mechanism.Methods:Sixty TIA patients were randomly divided into a control group and an observation group, each of 30. Another 30 healthy counterparts were selected to form a healthy control group. All of the TIA patients were given routine medication to lower blood pressure and improve brain function, while the observation group was additionally provided with enriched rehabilitation training for 12 weeks. Before and after the intervention, the gait and cognitive functioning of all of the subjects were quantified and their event-related potentials (P300s) and serum brain-derived neurotrophic factor (BDNF) levels were also measured.Results:Before the treatment there were significant differences between the TIA groups and healthy controls in all of the measurements, but there were no significant differences between the control and observation groups. After the treatment, no significant improvement was observed in any of the control group′s results, but there was significant improvement in the observation group′s gait parameters, cognitive functioning, average serum BDNF concentration and in the average latency and amplitude of its P300 signals.Conclusions:Enriched rehabilitation can improve the gait of TIA patients, perhaps through increasing their serum BDNF concentration and improving their cognition.
