A case report of intracranial infection caused by Aggregatibacter aphrophilus
10.3760/cma.j.cn113694-20210907-00619
- VernacularTitle:嗜沫凝聚杆菌致颅内感染1例
- Author:
Siyu YU
1
;
Yuhua SUN
;
Yabo WANG
;
Xin JIANG
;
Xiangshu CHENG
;
Houting ZHENG
;
Chen LI
;
Yalin LIU
Author Information
1. 河南大学淮河医院神经内科，开封475000
- Keywords:
Haemophilus paraphrophilus;
Central nervous system bacterial infections;
Metagenomic next-generation sequencing
- From:
Chinese Journal of Neurology
2022;55(5):506-510
- CountryChina
- Language:Chinese
-
Abstract:
Aggregatibacter aphrophilus is a member of the normal flora of the human oral cavity and pharynx, a Gram-negative fastidous bacteria, belonging to agglomerates, which is a normal mixed oropharyngeal flora in humans, most commonly colonized on the surface of oral mucosa. This bacterial infection is rare in clinical practice, and it is difficult to culture and identify the bacteria, which is easy to be missed. A patient with intracranial infection was admitted to Huaihe Hospital, who showed fever and headache as the main clinical manifestations, and Aggregatibacter aphrophilus was detected by the metagenomic next-generation sequencing of cerebrospinal fluid. The patient′s symptoms were significantly improved after anti-infection treatment.
