A case of diffuse leptomeningeal glioneuronal tumor resembling meningitis
10.3760/cma.j.cn113694-20210917-00647
- VernacularTitle:类脑膜炎表现的弥漫性软脑膜胶质神经元肿瘤1例
- Author:
Zixuan ZHANG
1
;
Jianrui LI
;
Yunfei HAN
;
Wusheng ZHU
;
Hao PAN
;
Nanyun LI
;
Zhiqiang ZHANG
Author Information
1. 东部战区总医院放射诊断科，南京 210002
- Keywords:
Brain neoplasms;
Neuroglia;
Neurons;
Meningitis;
Magnetic resonance imaging
- From:
Chinese Journal of Neurology
2022;55(4):358-362
- CountryChina
- Language:Chinese
-
Abstract:
Diffuse leptomeningeal glioneuronal tumor (DLGNT) is a rare, low-grade neoplasm, which is newly categorized into the neuronal and mixed neuro-glial tumor in 2016. The most characteristic imaging findings are diffuse leptomeningeal thickening and enhancement with multiple minor cysts. This article described a case with DLGNT mimicking meningitis, whose cystic lesions were not obvious, with swollen multiple lobes cortex, gyri form cortical calcification and enhanced meninges. Meningeal irritation sign repeated attacks and the clinical symptoms gradually improved after steroid pulse therapy. The biopsy and immunohistochemistry staining were diagnosed as DLGNT. The imaging features and clinical data of this case were analyzed to improve the understanding of the disease in clinical practice.
