Artery stenosis in renal grafts from infantile donors to adult recipients
10.3760/cma.j.cn421203-20211007-00245
- VernacularTitle:成人移植婴幼儿供肾术后移植肾动脉狭窄
- Author:
Jing CHEN
1
;
Xiangjun DONG
;
Qiuxiang XIA
;
Jingtao PENG
;
Xianpeng ZENG
;
Hanying LI
;
Chen GUO
;
Hua YANG
;
Heng LI
;
Zhendi WANG
Author Information
1. 华中科技大学同济医学院附属协和医院泌尿外科，武汉 430022
- Keywords:
Kidney transplantation;
Renal graft artery stenosis;
En-bloc double renal transplantation
- From:
Chinese Journal of Organ Transplantation
2022;43(1):25-29
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the clinical characteristics, causes, diagnosis and treatment of transplant renal artery stenosis after pediatric-to-adult kidney transplantation.Methods:Between July 2014 and March 2019, clinical data were retrospectively reviewed for 25 en-bloc and 27 single kidney transplant cases.Results:One en-bloc(4.0%)and two single kidney recipients(7.4%)were diagnosed as renal artery stenosis at Month 13-23 months post-transplantation.It was higher than the rate of stenosis in adult-to-adult transplant cases(1.1%)during the same period.As compared with recipients without stenosis, stenotic ones had younger pediatric donors( P<0.05)and yet similar body weight of donors as well as recipients( P>0.05). The inner diameters of stenonotic sites were(1.40-1.63)mm and predominant stenotic site was proximal renal artery rather than anastomotic site.The remaining parts of major renal arteries varied from 2.31 to 4.93 mm in diameter.It was normal in children with a corresponding age.All three cases responded well to percutaneous transluminal angioplasty and stenting. Conclusions:The cause of stenosis may be an undeveloped local artery diameter due to extensive tissue dissection around artery.Therefore cautious selections of infantile single renal graft for adult recipients and preserving surrounding tissue of renal artery assist in the prevention of graft arterial stenosis.
