Laparoscopic radical resection for gallbladder cancer
10.3760/cma.j.cn113855-20210817-00491
- VernacularTitle:腹腔镜胆囊癌根治术的临床疗效分析
- Author:
Jingyun CHEN
1
;
Guoping DING
;
Xiao LIANG
;
Bo SHEN
;
Liping CAO
Author Information
1. 浙江大学医学院附属邵逸夫医院普外科，杭州 310016
- Keywords:
Gallbladder neoplasms;
Prognosis;
Radical resection;
Laparoscope
- From:
Chinese Journal of General Surgery
2022;37(5):339-343
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the feasibility and clinical efficacy of laparoscopic radical cholecystectomy(LRC) for gallbladder cancer.Methods:The clinical data of 247 patients with gallbladder cancer who underwent radical resection from Jan 2013 to Dec 2019 at Department of General Surgery, Sir Run Run Shaw Hospital affiliated to Zhejiang University School of Medicine was analyzed retrospectively. After propensity score matching, 54 patients were included in laparoscopic group and 103 in laparotomy group. The clinicopathological characteristics and the short- and long-term outcomes were compared.Results:Compared to the laparotomy group, patients in the laparoscopic group had less intraoperative blood loss [100(50,200)ml vs. 200(100,300) ml, Z=4.105, P<0.001], earlier postoperative oral diet[1.0(1.0,2.0) d vs. 2.0(1.0,4.0) d, Z=4.157, P<0.001]and drainage removal[6.5(4.0,12.5) d vs. 9.0(6.0,16.0) d, Z=2.769, P=0.006], shorter hospital stay[7.0(5.0,9.3) d vs. 9.0(8.0,14.0) d, Z=3.923, P<0.001]. The number of lymph node dissection in laparoscopic group was significantly lesser than that in open group [6(4,9) vs. 8(5,12), Z=2.639, P=0.008]. There were no significant differences between the two groups in postoperative complications, short-term and long-term survival outcomes. Conclusions:Laparoscopic radical surgery for gallbladder cancer is as safe and feasible, and identical survival prognosis as open surgery, and moreover a less traumatic procedure.
