Analgesic modalities for ambulatory laparoscopic cholecystectomy
10.3760/cma.j.cn113855-20210618-00371
- VernacularTitle:日间腹腔镜胆囊切除术的镇痛方式探讨
- Author:
Liang SUN
1
;
Zhengyi WU
;
He HUANG
;
Xiangbao YIN
Author Information
1. 南昌大学第二附属医院肝胆外科，南昌 330000
- Keywords:
Cholecystectomy,laparoscopic;
Ambulatory surgical procedures;
Multimodal analgesia;
Ropivacaine;
Analgesic pump
- From:
Chinese Journal of General Surgery
2022;37(4):265-270
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the analgesic methods in ambulatory laparoscopic cholecystectomy (LC) patients.Methods:Three hundred patients were randomly divided into six groups receiving different analgesic regimen. VAS scores, postoperative blood pressure, CRP, IL-6, and the occurrence of postoperative adverse effects were recorded at 2, 4, 8, and 12 h postoperatively.Results:The success rate of ambulatory LC in this study was 66.22%. The dynamic VAS scores of patients in each group gradually decreased with time elapsing, with groups B and C being significantly lower than group A at 2 h and 4 h postoperatively ( P<0.05). Groups D, E and F were significantly different from group A at all postoperative time points ( P<0.05). There was a statistically significant difference at 8 h and 12 h postoperatively in group B vs. group D and group C vs. group E (all P<0.05). There was significant difference at the 12 h postoperatively between groups (B and C) compared to group F ( P<0.05). There was a significant difference in CRP and IL-6 between the groups (all P<0.05). Postoperative dizziness, nausea and delayed discharge were significantly higher in patients using analgesic pumps ( P<0.05). Conclusion:Local infiltration of ropivacaine combined with postoperative parecoxib sodium drip is a recommended analgesic regimen.
