Study on the prognostic value of circulating tumor cells in colorectal cancer patients

VernacularTitle:循环肿瘤细胞预测结直肠癌患者预后的价值
Author: Junhui YU ¹ ; Yanyan BAI ; Lan JIN ; Hongwei YAO ; Jin WANG ; Zhongtao ZHANG ; Yingchi YANG
Author Information

1. 首都医科大学附属北京世纪坛医院腹膜肿瘤外科，北京　100038
Keywords: Colorectal neoplasms; Tumor cells, circulating; Prognosis; Forecasting
From: Chinese Journal of General Surgery 2022;37(4):245-249
CountryChina
Language:Chinese
Abstract: Objective:To explore the prognostic value of circulating tumor cell (CTC) for colorectal cancer.Method:We analyze the correlation between CTC and clinicopathological data, survival curve and overall survival.Results:The positive rates of preoperative and postoperative CTC in 181 colorectal cancer patients were 66.3% and 65.7% respectively ( χ2=0.012, P=0.912). The postoperative CTC positive rates for recurrence and non-recurrence of stage Ⅱ colorectal cancer were 29.2% and 8.0%, respectively ( χ2=4.303, P=0.038). The progress free survuval of CTC-positive and CTC-negative in postoperative stage Ⅱ colorectal cancer patients were 28.7 months and 34.0 months, respectively ( χ2=4.096, P=0.043). Conclusion:Postoperative CTC detection has predictive prognostic value for patients with stage Ⅱ colorectal cancer.