Prognostic significance of BISAP combined with intra-abdominal pressure measurement in acute pancreatitis
10.3760/cma.j.cn113855-20210506-00279
- VernacularTitle:急性胰腺炎严重程度临床指数联合腹内压测定对胰腺炎严重程度及预后的预测价值
- Author:
Lijun CAO
1
;
Lu FU
;
Mingjuan LI
;
Zhonghua LU
;
Yun SUN
Author Information
1. 安徽医科大学第二附属医院重症医学科,合肥 230601
- Keywords:
Pancreatitis,acute necrotizing;
Pressure;
Bedside index for severity in acute pancreatitis
- From:
Chinese Journal of General Surgery
2022;37(2):118-121
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the predictive value of intra-abdominal pressure (IAP) combined with bedside index for severity in acute pancreatitis (BISAP) score on the severity and prognosis of acute pancreatitis (AP).Methods:In this retrospective study, 204 AP patients admitted to the Department of ICU, Second Hospital of Anhui University from Jan 2015 to Dec 2020 were divided based on the severity: into SAP group (145 cases) and Non-SAP group (59 cases) with end point survival (177 cases) and death (27 cases). The receiver operating characteristic (ROC) curves were drawn, and the predictive value of IAP, BISAP score and I-B (IAP and BISAP scores) in the severity and the prognosis of AP was studied. Medcalc software was used to compare the areas under ROC curve for different predictors.Results:IAP and BISAP scores increased with the severity of AP ( P<0.001), the area under the ROC curve (AUC) was 0.791, 0.749 and 0.907 respectively,comparison of area under ROC curve showed that I-B combined assessment was superior to IAP value and BISAP score alone in predicting severity ( P<0.05). IAP and BISAP scores were higher in the death group than in the survival group ( P<0.001). The ROC curve results of IAP, BISAP score and I-B combined on the prognosis of AP showed that the AUC was 0.773, 0.841 and 0.950, respectively,comparison of area under ROC curve showed that I-B combined assessment was superior to IAP and BISAP score alone in predicting prognostic value ( P<0.05). Conclusion:Both IAP and BISAP scores can better predict the severity of and the prognosis of AP, and the combination of IAP and BISAP score is more valuable for prediction of prognosis in AP.