Clinical features and surgical treatment of abdominal unicentric Castleman's disease

VernacularTitle:腹部局灶型Castleman病的临床特点与外科治疗
Author: Shimeng HUANG ¹ ; Xiaozhi LU ; Kuirong JIANG ; Yi MIAO ; Jishu WEI
Author Information

1. 南京医科大学第一附属医院胰腺中心，南京　210029
Keywords: Giant lymph node hyperplasia; Surgical procedures,operative; Lesion,unicentric
From: Chinese Journal of General Surgery 2022;37(1):10-12
CountryChina
Language:Chinese
Abstract: Objective:To summarize the clinical manifestations, diagnosis and surgical treatment of abdominal unicentric Castleman's disease.Methods:The clinical data of abdominal unicentric Castleman's disease cases admitted to the General Surgery Department of the First Affiliated Hospital,Nanjing Medical University from Jan 2009 to Dec 2019 was retrospectively analyzed.Results:A total of 18 patients were included with definite pathological diagnosis. The main complaint was abdominal pain and discomfort (50%, 6/12), dizziness and fatigue (25%, 3/12), multiple rash with oral ulcer (16.7%, 2/12) and weight loss (8.3%, 1/12). All patients received surgical resection. Postoperative pathology showed clear vascular type in 15 patients and plasma cell type in 3 patients. There were no major complications nor mortality.Conclusion:Abdominal unicentric Castleman's disease has diverse clinical manifestations, which was difficult for preoperative diagnosis, postoperative prognosis is satisfactory.