Value of ultrasonography, radionuclide imaging and CT in preoperative location diagnosis of primary hyperparathyroidism
10.3760/cma.j.cn113855-20210518-00304
- VernacularTitle:超声、核素及CT对原发性甲状旁腺功能亢进症术前定位诊断价值的研究
- Author:
Qiqi XU
1
;
Na KONG
;
Chunrui LIANG
;
Aimin CUI
;
Ziqin ZHANG
;
Shen TAN
;
Nan BAI
Author Information
1. 北京积水潭医院（北京大学第四临床医学院）普通外科 100035
- Keywords:
Hyperparathyroidism, primary;
Ultrasound, Doppler, color;
Radionuclide imaging;
Tomography, X-ray computer
- From:
Chinese Journal of General Surgery
2021;36(12):922-925
- CountryChina
- Language:Chinese
-
Abstract:
Objectiv:To evaluate ultrasound, radionuclide imaging and CT in preoperative localization diagnosis of primary hyperparathyroidism (PHPT).Method:A total of 170 PHPT patients admitted to the hospital between Jan 1992 and Dec 2020 were analyzed retrospectively. The preoperative localization diagnostic efficacy of ultrasonography, radionuclide and CT alone and in combination was compared in groups.Results:The overall sensitivity of ultrasound, radionuclide and CT were 82.13%,80.43% and 75.74%. For normal positioned parathyroid adenoma: as for sensitivity of location diagnosis, ultrasound (86.67%) was higher than radionuclide (81.82%, P<0.05) and CT (80.59%, P<0.05), ultrasound/CT parallel test (94.70%, P<0.05) was higher than ultrasound alone. For specificity of location diagnosis, radionuclide (97.78%) was higher than ultrasound (91.62%) and CT (93.39%), both ultrasound/radionuclide series tests (99.00%, P<0.001)and ultrasound/CT series tests (96.94%, P<0.001) were higher than ultrasound alone. In case of ectopic parathyroid adenoma and parathyroid hyperplasia: the sensitivity and specificity of radionuclide seemed higher than ultrasound and CT. Conclusions:Ultrasound is the first choice for preoperative location diagnosis of PHPT. Ultrasound combined with radionuclide or CT can significantly improve the diagnostic efficiency of parathyroid lesions.
