Long-term clinical evaluation on total parathyroidectomy in patients with secondary hyperparathyroidism
10.3760/cma.j.cn113855-20210610-00290
- VernacularTitle:甲状旁腺全切除术治疗继发性甲状旁腺功能亢进症患者术后远期疗效分析
- Author:
Linfeng WEI
1
;
Runsheng LI
;
Hui ZHAO
;
Xin ZHENG
;
Guoqiang HAO
;
Zhihui DENG
;
Zhuangjie XING
Author Information
1. 大连大学附属中山医院普通外科，辽宁省 116001
- Keywords:
Hyperparathyroidism,secondary;
Parathyroidectomy;
Kidney failure,chronic;
Parathyroid hormone
- From:
Chinese Journal of General Surgery
2021;36(12):919-921
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and long-term effect of total parathyroidectomy in patients with secondary hyperparathyroidism.Methods:One hundred fifty-four patients with secondary hyperparathyroidism who underwent total parathyroidectomy in Zhongshan Hospital,Dalian University from Mar 2012 to Mar 2018 were followed up for 3-9 years,including the level of iPTH, serum calcium and phosphorus and dosing of calcium supplement.Results:Among the 154 patients, the iPTH level in 149 patients fluctuated within 15-60 pg/ml. After oral calcium carbonate, the blood calcium fluctuated in 1.8-2.4 mg/ml, and serum phosphorus was 0.8-1.6 mg/ml. The level of iPTH in 5 patients was between 80-150 pg/ml, which was higher than the normal value 10-70 pg/ml. The clinical symptoms of all patients were significantly relieved.Conclusion:Total parathyroidectomy is safe and reliable in the treatment of secondary hyperparathyroidism with low recurrence rate and stable long-term effect.
