Background Parenchymal Enhancement on Breast MRI in Breast Cancer Patients : Impact on Biopsy Rate and Cancer Yield.
10.13104/jksmrm.2013.17.3.224
- Author:
Tae Yun KIM
1
;
Sung Hun KIM
;
Jee Eun BAIK
;
Yun Joo KIM
;
Bong Joo KANG
Author Information
1. Department of Radiology, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Korea. rad-ksh@catholic.ac.kr
- Publication Type:Original Article
- Keywords:
Breast;
Magnetic resonance imaging;
Image-guided biopsy;
Breast cancer
- MeSH:
Biopsy;
Breast;
Breast Neoplasms;
Humans;
Image-Guided Biopsy;
Magnetic Resonance Imaging
- From:Journal of the Korean Society of Magnetic Resonance in Medicine
2013;17(3):224-231
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: To evaluate the potential effects of background parenchymal enhancement of MR imaging in diagnosed breast cancer patients on the rate of additional biopsy and resultant cancer yield. MATERIALS AND METHODS: 322 patients who were diagnosed with breast cancer and had undergone breast MR imaging were included in this study. Two radiologists reviewed the MRI for degree of background parenchymal enhancement and additional suspicious lesions described as BI-RADS category 4 or 5 on radiologic reports. Biopsy was done for these lesions, pathology reports were reviewed to calculate the cancer yield. RESULTS: Background parenchymal enhancement of MR imaging in a total of 322 patients were classified as minimal degree 47.5%, mild degree 28.9%, moderate degree 12.4% and marked degree 11.2%. Among these 332 patients, MR imaging of 70 patients showed additional suspicious malignant lesions described as BI-RADS category 4 or 5, and consequently, 66 patients underwent biopsy. Biopsy rates in those with minimal or mild background parenchymal enhancement and those with moderate and marked background parenchymal enhancement were 19.9% and 22.3% (p-value 0.77) respectively. Cancer yields in those with minimal or mild background parenchymal enhancement and those with moderate and marked background parenchymal enhancement were 6.5% and 5.2% (p value 0.88) respectively. Both these results did not show stastically significant difference between the two groups. CONCLUSION: The degree of background parenchymal enhancement in MR imaging of breast cancer patients did not significantly impact additional biopsy rates or cancer yields.
