Role of autonomic nerves in immune imbalance in atopic dermatitis
- VernacularTitle:自主神经在特应性皮炎免疫失调中的作用
- Author:
Su YU
1
;
Tianze YU
;
Wei LI
Author Information
- Keywords: Dermatitis, atopic; Autonomic nervous system; Neuroimmunomodulation; Barrier immunity
- From: Chinese Journal of Dermatology 2022;55(4):362-365
- CountryChina
- Language:Chinese
- Abstract: The skin is rich in nerve terminals, among which autonomic nerves closely interact with keratinocytes and immune cells. The autonomic nerves are critical to skin physiological function. Patients with atopic dermatitis exhibit reduced autonomic innervation, accompanied by autonomic nerve dysfunction such as sweating disorder. Restoration of autonomic neurological function can ameliorate atopic dermatitis. This review summarizes the structure and physiological function of skin autonomic nerves, autonomic neurological abnormalities in atopic dermatitis, and possible therapeutic strategies.
