Bullous pemphigoid and its immune-mediated comorbidities
- VernacularTitle:大疱性类天疱疮合并其他免疫性疾病研究进展
- Author:
Wenling ZHAO
1
;
Yuyan YANG
;
Li LI
;
Hongzhong JIN
Author Information
- Keywords: Pemphigoid, bullous; Immune system diseases; Cross reactions; Epitope spreading; Multiple autoimmune syndrome
- From: Chinese Journal of Dermatology 2022;55(2):177-181
- CountryChina
- Language:Chinese
- Abstract: Bullous pemphigoid (BP) can be comorbid with a variety of immune diseases, such as immune skin diseases (psoriasis, vitiligo, alopecia areata and various other immune bullous diseases) , immune digestive diseases (inflammatory bowel disease, primary biliary cirrhosis) , autoimmune thyroid diseases, autoimmune rheumatic diseases (rheumatoid arthritis, dermatomyositis, scleroderma and systemic lupus erythematosus) , immune renal diseases (immune nephropathy, renal allograft rejection) and acquired hemophilia A. The above comorbidities markedly affect the quality of life of and treatment options for patients. This review elaborates on currently reported immune diseases associated with BP and their concomitant mechanisms.
