The preliminary study of Neuroform EZ stent in the treatment of severe intracranial atherosclerotic stenosis
10.3760/cma.j.cn112138-20210427-00310
- VernacularTitle:Neuroform EZ支架在重度颅内动脉粥样硬化性狭窄患者中的初步临床研究
- Author:
Chengzhe FAN
1
;
Lifeng WANG
;
Yudong MA
;
Xu GUO
;
Nan ZHANG
Author Information
1. 首都医科大学附属北京安贞医院神经介入科，北京100029
- Keywords:
Intracranial arteriosclerosis;
Atherosclerosis;
Endovascular procedures;
Stents
- From:
Chinese Journal of Internal Medicine
2022;61(3):304-309
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the safety and clinical efficacy of Neuroform EZ stent in the treatment of severe intracranial atherosclerotic stenosis (ICAS).Methods:A total of 36 patients with severe ICAS receiving Neuroform EZ stent angioplasty were retrospectively analyzed at Beijing Anzhen Hospital from July 2018 to January 2020. Digital subtraction angiography (DSA) before endovascular intervention confirmed the diagnosis. Follow-up information was reviewed by neurologists at 30 days and 6 months after the procedure. The primary endpoints were transient ischemic attack (TIA), ischemic or hemorrhagic stroke and death caused by any reason within 30 days.Results:The overall technical success rate was 100%. The median stenosis rate was reduced from 93.6%±4.5% to 18.8%±11.2% ( t=37.36, P<0.001).Primary endpoint event was not reported. During follow-up, one patient developed TIA and no death or ischemic stroke was observed. No in-stent restenosis at six months occurred. Conclusion:Neuroform EZ stent is safe and effective in patients with severe ICAS. However, perspective studies need to be operated for further validation via long-term follow-up.
