Bilateral adrenal hemorrhage caused by anticoagulant therapy after joint replacement surgery: One case report and literature review
10.3760/cma.j.cn311282-20210511-00289
- VernacularTitle:关节置换术后抗凝药物致双侧肾上腺出血一例报告并文献复习
- Author:
Weiguan DU
1
;
Ran LU
;
Ye LIU
;
Haining WANG
;
Hongwei GAO
;
Tianpei HONG
Author Information
1. 北京大学第三医院内分泌科 100191
- Keywords:
Adrenal hemorrhage;
Primary adrenal insufficiency;
Oral anticoagulants;
Rivaroxaban;
Total knee arthroplasty
- From:
Chinese Journal of Endocrinology and Metabolism
2022;38(3):244-248
- CountryChina
- Language:Chinese
-
Abstract:
Bilateral adrenal hemorrhage is a rare cause of primary adrenal insufficiency, and bilateral adrenal hemorrhage due to anticoagulant use is even rarer. We describe the case of a 62-year-old woman receiving post total knee arthroplasty anticoagulant therapy who presented fever, vomitting, stomachache, and severe fatigue on the 8th day. It was until 4 months later that the patient was finally diagnosed with adrenal insufficiency resuting from bilateral adrenal hemorrhage, her symptoms were relieved by glucocorticoid replacement therapy. In order to promote the awareness, diagnosis, and mangement of post-surgery anticoagulants induced bilateral adrenal hemorrhage, the clinical characteristics of the reported cases were summarized and analyzed.