Value of sugammadex for ultra-fast-track anesthesia in pediatric patients undergoing surgery for correction of congenital heart disease
10.3760/cma.j.cn131073.20201020.01215
- VernacularTitle:舒更葡糖钠用于先天性心脏病矫治术患儿超快通道麻醉的价值
- Author:
Yan JIANG
1
;
Rong WEI
;
Rufang ZHANG
;
Xiaobing LI
;
Ruidong ZHANG
;
Jijian ZHENG
Author Information
1. 上海交通大学医学院附属上海儿童医学中心麻醉科 200127
- Keywords:
Child;
Anesthesia, general;
Heart defects, congenital;
Sugammadex
- From:
Chinese Journal of Anesthesiology
2021;41(12):1471-1474
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the value of sugammadex for ultra-fast-track anesthesia in pediatric patients undergoing surgery for correction of congenital heart disease.Methods:Forty pediatric patients of both sexes, aged 1-6 yr, with American Society of Anesthesiologists physical status Ⅱ, scheduled for elective surgery for correction of congenital heart disease, were enrolled in this study and randomly assigned into sugammadex group (group S) and control group (group C) with a random number table.Sugammadex 4.0 mg/kg was injected intravenously to reverse neuromuscular relaxation in group S and the equal volume of normal saline was administrated in group C when the train-of-four (TOF) count was 0 and post-tetanic count was 1 or 2 during recovery from anesthesia.The recovery time of TOF ratio to 25%, 75% and 90%, the extubation time and the success rate of ultra-fast-track anesthesia were recorded.Results:Compared to group C, sugammadex significantly shortened the recovery time of TOF ratio to 25%, 75% and 90% and the extubation time in group S ( P<0.05); Furthermore, the success rate of ultra-fast-track anesthesia reached 100% in group S compared to 0% in group C. Conclusion:Intravenous administration of sugammadex 4.0 mg/kg significantly shortens the recovery time of neuromuscular relaxation and extubation time and enhances the success rate of ultra-fast-track anesthesia in pediatric patients undergoing surgical correction of congenital heart disease.
