Effects of aging on nutrition and immune function among elderly men
10.3760/cma.j.issn.0254-9026.2022.05.012
- VernacularTitle:增龄对老年男性营养和免疫功能的影响
- Author:
Dongni YU
1
;
Lei QIU
;
Haimei QI
;
Gang ZHOU
;
Xianbo ZHANG
;
Yan ZHOU
;
Qi PAN
;
Lixin GUO
Author Information
1. 北京医院内分泌科 国家老年医学研究中心，中国医学科学院老年医学研究院，北京 100730
- Keywords:
Age factors;
Nutritional status;
Immunity
- From:
Chinese Journal of Geriatrics
2022;41(5):565-569
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze changes in nutritional status and immune function of elderly men receiving regular physical examinations, and to investigate the effects of aging on the nutritional status and immune function among elderly men.Methods:A total of 209 elderly men aged 60-101(72.9±11.5)years and receiving regular physical check-ups were enrolled.All research subjects were subjected to nutritional risk screening(NRS2002)and monitoring of nutrition and immune-related indicators, including routine blood work, blood biochemistry, immunoglobulin and T lymphocyte subsets.Results:Body weight, body mass index, hemoglobin, total protein, albumin and serum iron of elderly men decreased with age( F=21.754, 6.257, 47.528, 12.285, 18.397, 18.667, all P<0.001), with those aged 80 and above showing more significant decline and a greater proportion with malnutrition( χ2=77.134, P<0.001). The B lymphocyte counts of elderly men aged 80 and above were significantly lower( P<0.05)while serum IgA and IgG levels were significantly higher( F=3.110, 3.866, P=0.047, 0.022)than those of the 70-79 year old group.In addition, the B lymphocyte count and B lymphocyte ratio in malnourished elderly men were significantly lower( t=2.512, 2.874, P=0.013, 0.005), and IgA was significantly increased( t=2.513, P=0.017), compared with those with normal nutrition. Conclusions:The risk of malnutrition and reduced immune function among elderly men aged 80 years and above is significantly increased, and assessment and screening of the risk of malnutrition in the elderly should be stressed.
