A flowchart for the diagnosis and differential diagnosis of post-stroke aphasia types in the Chinese language and treatment of post-stroke aphasia
10.3760/cma.j.issn.0254-9026.2022.04.025
- VernacularTitle:汉语卒中后失语症失语类型的诊断、鉴别诊断流程图和卒中后失语症的治疗
- Author:
Yinhua WANG
1
;
Wanliang DU
;
Xiaona YANG
;
Jun YAN
;
Wei SUN
;
Jing BAI
;
Jiong ZHOU
;
Aihong ZHOU
;
Jianping NIU
;
Chuanling LI
;
Jian WANG
Author Information
1. 北京大学第一医院神经内科，北京 100034
- Keywords:
Post-stroke aphasia;
PSA types in Chinese;
Dichotomy;
Four elements;
Diagnosis;
Treatment
- From:
Chinese Journal of Geriatrics
2022;41(4):488-496
- CountryChina
- Language:Chinese
-
Abstract:
This article aims to comprehensively review the concept, etiology, classification, classical cortical mapping, assessment, a proposed flowchart for the diagnosis and differential diagnosis, treatment, rehabilitation, mechanisms of development and recovery, prognosis, and influencing factors for post-stroke aphasia(PSA)types in the Chinese language.We emphasize the necessity and significance of neuroimaging assessment of the brain and blood vessels and neuropsychological assessment in the diagnosis and differential diagnosis of PSA in Chinese.We also recommend and encourage the use of the dichotomies of internal vs.external and anterior vs.posterior as a starting point, based on the association of anatomical locations of the brain and blood vessels with brain language areas and language disorders.A classification system of PSA in Chinese developed from this approach in the form of a flowchart is well-suited for guiding the clinical treatment of cerebral stroke.Incorporating the "four elements" , the flowchart enables convenient diagnosis, classification and differential diagnosis of PSA in Chinese and facilitates targeted and personalized rehabilitation planning to benefit the patient.This article introduces the use of memantine, piracetam, donepezil and other drugs for PSA treatment, evaluates clinical trials on memantine conducted in China and abroad and its mechanisms of action for the treatment of PSA, and discusses how rehabilitation therapy achieves therapeutic effects.For the treatment of PSA, clinical research and practice using drugs such as memantine, piracetam and donepezil in combination with non-pharmacotherapy and rehabilitation training should be promoted.
