Application and efficiency of kidney-helping and blood-activating paste in senile diabetic kidney disease of Qi-Yin Deficiency Syndrome
10.3760/cma.j.issn.0254-9026.2022.04.019
- VernacularTitle:补肾活血贴在老年气阴两虚挟瘀证糖尿病肾脏疾病中的应用
- Author:
Yuqin ZHOU
1
;
Yaqing XU
;
Jiandi ZHENG
;
Fangfang CHEN
;
Sonsong ZHANG
Author Information
1. 浙江省中西医结合医院内分泌科，杭州 310003
- Keywords:
Qi-Deficiency;
Diabetic nephropathies;
Kidney-helping and blood-activating paste
- From:
Chinese Journal of Geriatrics
2022;41(4):456-459
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the application and efficiency of Bushen Huoxue Plaster in senile subjects with diabetic kidney disease with Qi-Yin Deficiency with Blood stasis.Methods:A total of 100 elderly diabetic kidney disease(DKD)patients with Qi-Yin deficiency and Blood stasis syndrome in Endocrinology Department of Zhejiang Province Traditional Chinese and Western Medicine Hospital from February 2020 to May 2021were randomly divided into observation group(n=50)receiving TonifyingKidney and Activating Blood Paste plus TCM directional drug penetration therapy instrument for 10 days and control group(n=50)receiving placebo paste plus TCM directional drug penetration therapy instrument for 10 d. Main symptom score, overall syndrome score, urinary albumin/ creatinine ratio were observed and recorded.Results:After treatment, the observation group versus the control groups showed the statistically significant improvement in dry mouth and pharynx[(0.06±0.24)versus(0.30±0.68)score point, in feeling tired[(0.49±0.76)versus(0.98±1.02)score point], in spontaneous sweating or sweating after exercise[(0.08±0.27) vs.(0.32±0.69)score point], in limb numbness[(0.49±0.64) vs.(0.83±0.93)score point], in urination obstruction[(0.20±0.53) vs.(0.55±0.92)score point], and in total syndrome score[(1.65±2.06) vs.(3.36±2.53)score point, (all P<0.05)].The mean Ridit value of urinary albumin/creatinine ratio decreased in the observation group of chronic kidney disease stage A2 was 0.595 being higher than 0.405 in the control group, and the difference was statistically significant( P<0.05). Conclusions:The kidney-helping and blood-activating paste can improve the clinical symptoms of senile patients, and may have a certain effect on improving the urine albumin/creatinine ratio of patients with early diabetic kidney disease, and it is worthy of clinical application.
