Consistency between multifrequency bioelectrical impedance analysis and dual-energy x-ray absorptiometry for muscle mass assessment in elderly patients with advanced chronic kidney disease
10.3760/cma.j.issn.0254-9026.2022.04.006
- VernacularTitle:多频生物电阻抗与双能X线法在进展期老年慢性肾脏病患者中肌肉量评定一致性比较
- Author:
Dongsheng CHENG
1
;
Qi ZHANG
;
Guihua JIAN
;
Niansong WANG
;
Zhi WANG
;
Junhui LI
Author Information
1. 上海市第六人民医院肾内科，上海 20023
- Keywords:
Chronic kidney disease;
Dual-energy X-ray absorptiometry;
Bioelectrical impedance analysis;
Sarcopenia
- From:
Chinese Journal of Geriatrics
2022;41(4):393-396
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the consistency between bioelectrical impedance analysis(BIA)and dual-energy X-ray absorptiometry(DXA)in skeletal muscle mass assessment in elderly patients with advanced chronic kidney disease(CKD), and to provide a basis for accurate clinical diagnosis of sarcopenia.Methods:Elderly patients with advanced CKD at the Department of Nephrology of Shanghai Sixth People's Hospital were included.Parameters for physical performance included handgrip strength and gait speed, and body muscle mass was measured by DXA and multifrequency BIA.The consistency between the two methods was assessed by the intraclass correlation coefficient, Bland-Altman analysis and kappa coefficient test.Results:This study included 67 elderly patients with advanced CKD with a mean age of(70.7±6.1)years and an average BMI of(24.6±3.5)kg/m 2.The proportion of enrolled male patients was 61.2% and the mean estimated glomerular filtration rate was(27.7±12.7)ml·min -1·1.73m -2.The intraclass correlation coefficients of muscle mass and appendicular skeletal-muscle mass index(ASMI)measured by BIA and DXA ranged from 0.81 to 0.90.Bland-Altman analysis showed that BIA overestimated muscle mass against DXA, and the mean difference in ASMI was(0.44±0.13)kg/m 2.In addition, there was a moderate agreement between the two measurement methods for determining muscle loss(Kappa=0.47). Conclusions:BIA and DXA offer a fair level of consistency in the assessment of muscle mass in elderly patients with advanced CKD.However, compared with DXA, BIA overestimates muscle mass in elderly patients with CKD.
