Research progress on mitochondrial dynamics and age-related diseases
10.3760/cma.j.issn.0254-9026.2022.03.025
- VernacularTitle:线粒体动力学与衰老相关疾病的研究进展
- Author:
Tingting HUANG
1
;
Danmei ZHANG
;
Guoxian DING
;
Juan LIU
Author Information
1. 南京医科大学第一附属医院/江苏省人民医院老年内分泌科，南京 210029
- Keywords:
Mitochondria;
Mitochondrial dynamics;
Aging
- From:
Chinese Journal of Geriatrics
2022;41(3):355-359
- CountryChina
- Language:Chinese
-
Abstract:
Mitochondrial dynamics regulates mitochondrial morphology and functions.Imbalance in mitochondrial dynamics with aging leads to mitochondrial dysfunction, accelerates the aging process and is closely related to the occurrence and progression of age-related diseases.However, the specifics of the relationship between aging and altered mitochondrial dynamics are still not fully understood.Here, we review the link between mitochondrial dynamics and aging, and discuss mechanisms underlying age-related diseases associated with altered mitochondrial dynamics, aiming to identify novel therapeutic targets and strategies for the management of age-related diseases.
