First Isolation of Streptococcus gallolyticus subsp. pasteurianus from a Korean Patient with Severe Septic Shock.
10.5145/KJCM.2011.14.4.144
- Author:
Seri JEONG
1
;
Ji Yeon PARK
;
Sang Hoon HAN
;
Yangsoon LEE
;
Dongeun YONG
;
Kyungwon LEE
;
Yunsop CHONG
Author Information
1. Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea. deyong@yuhs.ac
- Publication Type:Case Report
- Keywords:
Streptococcus gallolyticus subsp. pasteurianus;
Septic shock;
16S rRNA gene sequencing
- MeSH:
Agar;
Ampicillin;
Blood Urea Nitrogen;
Body Temperature;
C-Reactive Protein;
Catalase;
Creatinine;
Diarrhea;
Fever;
Genes, rRNA;
Gram-Positive Cocci;
Heart Rate;
Humans;
Hydrolysis;
Leucyl Aminopeptidase;
Middle Aged;
Pyrrolidinones;
Respiratory Rate;
Shock, Septic;
Sprains and Strains;
Streptococcus;
Sulbactam;
Vomiting
- From:Korean Journal of Clinical Microbiology
2011;14(4):144-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
A 60-year-old man presented with a 1-day history of fever, vomiting, and diarrhea. He was diagnosed with severe septic shock on the basis of a body temperature of 38.9degrees C, heart rate of 92/min, respiratory rate of 25/min, WBC count of 22,970/microL, C-reactive protein (CRP) level of 136 mg/L, blood urea nitrogen (BUN) of 34.0 mg/dL, and creatinine of 2.98 mg/dL. On blood culture, Gram-positive cocci were detected in all 6 bottles. Small grayish non-hemolytic colonies were found on blood agar plates after incubation at 37degrees C for 2 days. The isolates were negative for catalase and L-pyrrolidonyl-beta-naphthylamide hydrolysis, and positive for bile-esculin and leucine aminopeptidase activity. The strain was identified as Streptococcus gallolyticus subsp. pasteurianus using Vitek 2 GP II systems. We performed 16S rRNA gene sequencing and detected 100% identity with S. gallolyticus subsp. pasteurianus strain CIP 107122T (1,345/1,345-bp). The patient recovered after receiving ampicillin-sulbactam. This is the first report of phenotypic and genetic identification of S. gallolyticus subsp. pasteurianus causing severe septic shock in a Korean patient.
