Progress in application of hepatitis B virus core-associated antigen in differentiating natural stages of chronic HBV infection
10.3760/cma.j.issn.1674-2397.2022.01.011
- VernacularTitle:乙型肝炎病毒核心相关抗原在慢性HBV感染自然分期中的价值
- Author:
Min QUAN
1
;
Huichun XING
Author Information
1. 首都医科大学附属北京地坛医院肝病科，北京 100015
- Keywords:
Chronic HBV infection;
Hepatitis B virus core associated antigen;
Quantitative detection
- From:
Chinese Journal of Clinical Infectious Diseases
2022;15(1):57-60
- CountryChina
- Language:Chinese
-
Abstract:
Chronic HBV infection can generally be divided into four stages according to the natural course of disease. Clinically, the determination of different natural stages of chronic HBV infection is crucial for patients to start antiviral therapy and to avoid missing the antiviral opportunity and progressing to cirrhosis. In particular, it is a challenge for clinicians to distinguish the immune control stage from the reactive stage. As a novel marker of HBV, the quantitative detection of HBV core-associated antigen (HBcrAg) is of value for the identification of the HBV infection stages. This article reviews the research progress of HBcrAg in the identification of different stages of chronic HBV infection.
