Relationship between the high sensitivity C-reactive protein and anxiety levels in hospitalized patients with cardiovascular-related diseases and hypertension
10.3760/cma.j.cn115624-20211227-00790
- VernacularTitle:存在高血压的心血管相关疾病住院患者超敏C-反应蛋白与焦虑水平的关系
- Author:
Qi LI
1
;
Hong CAO
;
Ming GU
;
Jiang WAN
;
Chuyun WANG
;
Run YUAN
;
Lin LI
;
Xiang LI
;
Jichun CHEN
Author Information
1. 北京协和医学院 中国医学科学院阜外医院营养科，北京 100037
- Keywords:
Hypertension;
High sensitivity C-reactive protein;
Anxiety;
Interrelationship
- From:
Chinese Journal of Health Management
2022;16(5):303-307
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the relationship between the high sensitivity C-reactive protein (hs-CRP) and anxiety levels in patients hospitalized with cardiovascular-related diseases and hypertension.Methods:A total of 221 patients hospitalized with cardiovascular-related diseases in the Fuwai Hospital were selected by a voluntary sampling method from September to December 2021. Participants were divided into hypertensive and non-hypertensive groups ( n=119 and n=102) based on the diagnosis of hypertension in their inpatient medical records. Anxiety levels were assessed using the Zung Self-Rating Anxiety Scale, and the levels of serum hs-CRP were estimated by automatic immunoanalyzer. Multivariate logistic regression was used to analyze the relationship between hs-CRP and anxiety. Results:In the hypertensive group, the risk of anxiety in patients with abnormal hs-CRP (>3 mg/L) was 4.239 times (95% CI: 1.569-11.748, P=0.005) higher than those in normal hs-CRP (≤3 mg/L). In turn, compared with patients without anxiety, those with anxiety had 3.878 times greater probability of experiencing abnormal hs-CRP (95% CI: 1.495-10.062, P=0.005), while those with mild anxiety and moderate to severe anxiety had 4.525 times (95% CI: 1.392-14.714, P=0.012) and 3.286 times (95% CI: 0.911-11.357, P=0.070) greater odds of experiencing abnormal hs-CRP, respectively. No similar significant association was seen in the non-hypertensive group. Conclusion:There is an interrelationship between elevated hs-CRP and anxiety in hospitalized patients with cardiovascular-related diseases and hypertension.
