Research progress of polyetherketoneketone and its composites for orthopedic implant materials
10.3760/cma.j.cn121113-20211105-00638
- VernacularTitle:聚醚酮酮及其复合材料用于骨科植入物的研究进展
- Author:
Yujiong CHEN
1
;
Zhaoxiang PENG
Author Information
1. 宁波大学附属李惠利医院关节与运动医学科，宁波 315040
- From:
Chinese Journal of Orthopaedics
2022;42(9):603-608
- CountryChina
- Language:Chinese
-
Abstract:
Polyetherketoneketone (PEKK) is a semi-crystalline linear thermoplastic polymer with two ketone bonds and one ether bond in the main chain structure. It has many advantages such as elastic modulus close to that of natural human bone, biocompatibility, good chemical stability, radiolucency, compatibility with MRI, etc, which make it a new biomaterial for the production of orthopedic implants. The development of PEKK composites with better bone bioactivity without compromising the original properties of PEKK through special material preparation processes has become a hotspot. PEKK composites are made by combining biological ceramics (hydroxyapatite, silicon nitride) and metals with good biocompatibility (aluminum, tantalum and titanium). These composites not only retain the elastic modulus similar to that of human bone, but also improve hardness, biocompatibility, antibacterial properties, and bone integration ability, and thus have great potential in the field of orthopedic implants. The application of PEKK and its composites in the orthopedic field was searched in PubMed, Embase, ScienceDirect, CNKI and Wanfang databases. The properties advantages and disadvantages of PEKK and its composite materials modified by various methods in the recnt years (e.g. modification doping mixture, modification of the surface by sulfonation, 3D printing and treatment by surface deposition) were analyzed to provide a reference for the preparation clinically usable orthopedic implants with different functions.
