Flow Cytometric DNA Content Analysis in uterine Cervical Cancer.
- Author:
Hey Won CHUNG
;
Ho Sun CHOI
- Publication Type:Original Article
- MeSH:
Aneuploidy;
Diploidy;
DNA*;
Flow Cytometry;
Lymph Nodes;
Neoplasm Metastasis;
Ploidies;
Uterine Cervical Neoplasms*
- From:Korean Journal of Gynecologic Oncology and Colposcopy
1994;5(3):49-53
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The DNA ploidy using fresh tissues from 304 cervial cancer were analyzed by flow cytometry in order to evaluate the correlation between DNA ploidy patterns and prognostic factors of uterine cervical cancer. There were l67 diploid cases(55%) and 137 aneuploid(45%). No significant correlation was noted in stage, age and lymph node metastases between diploid and aneuploid tumor. But S-phase fraction and DNA index were higher slightly in cases of lymph node metastases cornpaired to non-metastases. This results suggest that the DNA ploidy cannot be used as an independent prognostic fac- tor, but further evaluation will be needed in order to conclude definite relationship between prognoseic factor and S-phase fraction or DNA index.
