Clinical characteristics of patients with septated loculations of pyogenic liver abscesses
10.3760/cma.j.cn113884-20210914-00308
- VernacularTitle:分隔状肝脓肿的临床特征分析
- Author:
Zhaoqing DU
1
;
Miaomiao CHI
;
Yuxin LIN
;
Yunbing WU
;
Xilin GENG
;
Rongqian WU
Author Information
1. 陕西省人民医院肝胆外科，西安 710068
- Keywords:
Liver abscess;
Klebsiella pneumonia;
Septal lobulation;
Percutaneous drainage
- From:
Chinese Journal of Hepatobiliary Surgery
2022;28(4):259-263
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare clinical features of patients with pyogenic liver abscesses with and without septated lobulations.Methods:Patients diagnosed to have pyogenic liver abscesses who were treated in our hospital from January 2011 to March 2021 were enrolled into this retrospective study. There were 203 males and 132 females, with age of (56±14) years old. The patients were divided into two groups by findings on computed tomography and ultrasound into the septated lobulation group ( n=68) and the non-septated lobulation group ( n=267). The clinical data of these patients were compared. Results:In the septated lobulation group, the neutrophil count was 9.17(5.97, 12.33)×10 9/L and the TBil was 17.65(11.92, 27.84) μmol/L. These were significantly higher than the corresponding figures of 7.81(5.42, 10.81)×10 9/L, 12.90(9.00, 19.68) μmol/L, respectively in the non-septated lobulation group ( P<0.05). The difference in the maximum diameters of the septated lobulation group was also significantly larger than the non-septated lobulation group ( P=0.032). Additionally, pus culture showed the proportion of Klebsiella pneumoniae positive patients in the septated lobulation group was significantly higher than that in the non-septated lobulation group [41.18% (28/68) vs. 25.84% (69/267), P=0.013]. The use of fluoroquinolones in patients in the septated lobulation group was higher than that in the non-septated lobulation group [20.59% (14/68) vs. 10.11% (27/267), χ 2=5.54, P=0.019]. Conclusion:Compared to patients without septated lobulations, those with septated lobulations had a larger diameter of abscesses, a higher positive rate of Klebsiella pneumoniae on pus culture and a higher proportion of patients receiving fluoroquinolones.
