Advances in the pathogenesis of pancreaticobiliary maljunction
10.3760/cma.j.cn113884-20210831-00294
- VernacularTitle:胆胰合流异常发病机制的研究进展
- Author:
Lili CHENG
1
;
Yi ZHOU
;
Hui LIU
;
Yifa CHEN
Author Information
1. 鄂州市中心医院普外一科，鄂州 436000
- Keywords:
Common bile duct;
Pancreas;
Phospholipases A2;
Sphincter of Oddi
- From:
Chinese Journal of Hepatobiliary Surgery
2022;28(2):154-157
- CountryChina
- Language:Chinese
-
Abstract:
Pancreaticobiliary maljunction means the common bile duct and the main pancreatic duct in the duodenal wall, or is the formation of a long common channel leading to biliopancreatic reflux, resulting a series of biliopancreatic diseases, and even the occurrence of biliary malignancy. The pathogenesis of pancreaticobiliary maljunction is complex, involving biliary fluid dynamics, the activation of phospholipase A2, protease activation, amino acids, fat metabolism, gene mutation. This paper summarized the latest study of the pathogenesis of the pancreaticobiliary maljunction to let clinicians understand pancreaticobiliary maljunction diseases, and provide new treatment ideas.
