Study of 3D-printed multi-channel applicator in patients treated with brachytherapy after cervical cancer surgery
10.3760/cma.j.cn113030-20210712-00257
- VernacularTitle:3D打印多通道施源器在宫颈癌术后患者近距离治疗中研究
- Author:
Chengqiong TANG
1
;
Jiangping LIU
;
Kuerban GULINA
;
Hao LIU
;
Yaofeng CAO
;
Xiaofang ZHANG
;
Wei ZHONG
Author Information
1. 新疆医科大学附属肿瘤医院（第三临床医学院）放射物理技术科，乌鲁木齐 830011
- Keywords:
3D printing;
Multi-channel applicator;
Brachytherapy;
Inverse dose optimization
- From:
Chinese Journal of Radiation Oncology
2022;31(5):445-449
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the dosimetric difference between 3D-printed multi-channel applicator and conventional vaginal single-channel applicator for brachytherapy, aiming to provide guidance for patients receiving brachytherapy after cervical cancer surgery.Methods:From January 2019 to November 2020, 25 cervical cancer patients complicated with VAIN Ⅲ receiving 192Ir high-dose-rate brachytherapy after cervical cancer surgery were selected. Each patient was located by CT scanning with 3D-printed multi-channel applicator and conventional vaginal single-channel applicator, and corresponding plan and evaluation were carried out. The dose volume histogram (DVH) was obtained by inverse dose optimization algorithm. The dosimetric differences of high-risk clinical target volume (HRCTV), bladder and rectum during brachytherapy were compared with those of source applicators. The optimal treatment plan was selected. Results:D 90%, D 100%, V 100% and V 150% of the plans designed by 3D-printed individual multi-channel applicator had no significant differences compared with those designed by conventional single-channel applicator (all P>0.05). The bladder and rectal D 2cm 3 designed by 3D-printed multi-channel applicator were significantly lower than those using conventional single-channel applicator, and the differences were statistically significant (both P<0.05). Conclusion:The multi-channel individual applicator target made by 3D-printing technology has good conformal property, properly protects the bladder and rectum and possesses treatment advantages over conventional single-channel applicator.
